Answer:
extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.
Explanation:
One type of temperature change that inhibits enzyme activity is heating. Raising the temperature causes the molecules to vibrate faster. But when the temperature increases too much, the enzyme unfolds. This unfolding, called denaturation, makes the enzyme lose its three-dimensional shape and thus activity.
